Medical Disclaimer: This database is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any treatment.
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Showing 1 of 107 available treatments
Evidence by Condition
- POTS · EmergingSmall acute placebo-controlled crossover studies show less tachycardia, mainly in neuropathic POTS; a 2026 systematic review calls it a possible add-on, with low-certainty evidence.
- Long COVID · ExperimentalNo trials in Long COVID; support comes from a patient survey (TREATME) and clinical practice.
- ME/CFS · ExperimentalNo trials in ME/CFS; recommended in ME/CFS clinical guidance for orthostatic intolerance, extrapolating from POTS and orthostatic hypotension.
Symptoms Addressed
Orthostatic hypotensionOrthostatic intoleranceDizzinessTachycardiaFatigue
Potential Side Effects
Supine hypertensionScalp tinglingUrinary retentionPiloerection
Mechanism of Action
Alpha-1 adrenergic agonist; increases peripheral vascular resistance and venous return; raises standing blood pressure
Evidence Type(s)
Double-blind placebo-controlled crossover RCT, Cohort study, Large patient survey (TREATME Study), Clinical guideline recommendation
Key References
OTC Alternatives
Increased dietary sodium, electrolyte supplements, licorice root
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