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Showing 1 of 107 available treatments
Evidence by Condition
- ME/CFS · ExperimentalUncontrolled, unblinded studies only (n=86, 6 mg/week for 90 days; a 40-patient preprint) reported less fatigue and PEM.
- Long COVID · ExperimentalAnecdotal reports and patient surveys; a placebo-controlled RCT (NCT06960928) is underway.
Symptoms Addressed
FatiguePEMBrain fogMuscle weakness
Potential Side Effects
Mouth sores (mucositis)ImmunosuppressionDyslipidemiaWound healing impairmentGI symptomsInfection risk
Mechanism of Action
mTOR inhibitor; restores autophagy via ATG13 pathway; reduces chronic neuroinflammation; promotes mitophagy; reduces T cell exhaustion; antiviral at low doses
Evidence Type(s)
Uncontrolled observational trial (n=86), Anecdotal reports, Large patient survey (TREATME Study)
ClinicalTrials.gov
Key References
OTC Alternatives
Curcumin, resveratrol, EGCG, berberine, quercetin (weak mTOR modulation)
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